Nov 25, 2025Newly registered products’ active ingredient targets Colorado potato beetle
The EPA has registered 10 products containing the new active ingredient isocycloseram, a broad-spectrum contact insecticide proposed for use on agricultural crops, turf and ornamentals.
The Colorado potato beetle is among the target pests for products containing the active ingredient.
The isocycloseram registrations are supported by human health and ecological risk assessments as well as a biological evaluation under the Endangered Species Act (ESA), according to a statement on the EPA’s website. The agency did not identify risks of concern for aquatic and terrestrial plants, preliminarily concluding that the proposed use of isocycloseram may affect insect pollinators from spray application and aquatic invertebrates from spray, seed, and soil treatments.
Isocycloseram can also cause chronic risks to birds and mammals ingesting treated rapeseed.
EPA’s final biological evaluation predicts that the use of isocycloseram will not result in a likelihood of future jeopardy for the survival of any listed species or a likelihood of adverse modification for any designated critical habitat.
In June, the National Potato Council (NPC) submitted comments to EPA supporting the registration of this new insecticide.
“If cleared to enter the market, Isocycloseram would be an effective tool for potato producers across the United States struggling to protect their crops from the damaging Colorado potato beetle along with spider mites, potato leafhopper and thrips,” NPC said.
